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Signet ring cell carcinoma of the ampulla of Vater |
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| Authors: | García Aurora Burgos Arranz Eduardo Martín Sanz Rafael Rey Serrano Eva Marín Arranz María Dolores Martín Sanz-Agero Paloma González Bellido Elena Collantes Kreilinger José Juan Pozo Prianes Luis Asensio Juberías Luis Alberto Mata Robledo Juan Pedro Pérez Parga José Manuel Suárez Cabral José María Segura |
| Affiliation: | a Servicio de Aparato Digestivo, Hospital Universitario La Paz, Madrid, España b Servicio de Anatomía Patológica, Hospital Universitario La Paz, Madrid, España c Servicio de Cirugía General y Aparato Digestivo, Hospital Universitario La Paz, Madrid, España |
| Abstract: | IntroductionSignet ring cell carcinoma of the ampulla of Vater is a rare entity and less than 20 cases have been described in the literature. We report the cases of two patients with this disease and provide a literature review of previous studies.Case reportWe describe two patients with obstructive jaundice. Abdominal ultrasonography and abdominal computed tomography showed dilatation of the intrahepatic and common bile duct. Duodenoscopy indicated a protruding mass on the ampulla of Vater. Histopathological examination showed round cells and their nuclei were located on one side with prominent signet-ring features. One patient underwent a cephalic pancreatoduodenectomy with lymphadenectomy and the other a total pancreatectomy.DiscussionSignet ring cell carcinoma of the ampulla of Vater has only been described in isolated cases in the literature. Therefore, the clinicopathological features and prognosis of this disease have not yet been well defined. |
| Keywords: | Ampolla de Vater Carcinoma Cé lulas en anillo de sello Neoplasia |
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