Outcome of mother to infant acquired GBV-C/HGV infection. |
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| Authors: | G Zuin B Saccani S Di Giacomo E Tanzi A R Zanetti N Principi |
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| Institution: | Fourth Paediatric Department, Università di Milano, Istituto di Scienze Biomediche Sacco, Italy. |
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| Abstract: | Twelve children born to hepatitis C virus antibody GBV-C/HGV RNA positive mothers who acquired GBV-C/HGV infection by the vertical or perinatal route were studied. Most (91%) were persistently GBV-C/HGV RNA positive up to 12 months of age. Four out of six cases who acquired GBV-C/HGV alone had normal alanine amino transferase activities. Long lasting evidence of hepatocellular injury was detected only in children with GBV-C/HGV and hepatitis C virus and HIV coinfection. |
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