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| 高半乳糖血症对大鼠晶体上皮细胞膜泵功能的影响 | |
| 引用本文： | 颜京霞,宋秀君,刘佑兰.高半乳糖血症对大鼠晶体上皮细胞膜泵功能的影响[J].华北煤炭医学院学报,2003,5(3):277-278. |
| 作者姓名： | 颜京霞 宋秀君 刘佑兰 |
| 作者单位： | 1. 华北煤炭医学院基础部组胚学教研室,河北唐山,063000 2. 河北医科大学第三附属医院 3. 河北省唐山工人医院 |
| 摘 要： | ①目的 观察高半乳糖血症对大鼠晶体上皮细胞膜Na —K —ATP酶及Ca2 -ATP酶活性的影响。②方法 设置正常对照组与高半乳糖血症组。高半乳糖血症组腹腔注射D-半乳糖复制大鼠模型，采用无机磷法测定大鼠晶体上皮细胞膜两种酶的活性。③结果 高半乳糖血症组大鼠晶体上皮细胞膜Na -K -ATP酶活性先出现升高，然后下降；Ca2 -ATP酶活性别明显下降。④结论 高半乳糖血症致大鼠晶体周围微环境改变，晶体内多种氨基酶丢失，细胞遭受乳化性损伤，最终导致细胞膜酶活性改变。 |
| 关 键 词： | 高半乳糖血症 晶体 Na^＋－K^＋－ATP酶 Ca^2＋－ATP酶 大鼠 |
| 文章编号： | 1008-6633(2003)03-0277-02 |
| 修稿时间： | 2002年12月20 |
The effect of hypergalactonemia on the pump actinty of rat's Len epithelial membrane |
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| Yan Jingxia,Song Xiujun,Liu Youlan..The effect of hypergalactonemia on the pump actinty of rat''''s Len epithelial membrane[J].Journal of North China Coal Medical College,2003,5(3):277-278. | |
| Authors: | Yan Jingxia Song Xiujun Liu Youlan |
| Abstract: | Objective To observe hypergalactonemia's effect on the pump activity of rats' len epithelial membrane. Methods 38 rats(76 eyes) were divided into two groups,nomal control and hypergalactonemia group. After in-trap galactose injected,lens epithelial membrane were obtained. The activities of Na + -K + -ATPase ,Ca2+-ATPase were measured. Result The activity of Na+-K+-ATPase rised at first,then lowed,Ca2+-ATPase lowed obviously. Conclusion Hypergalactonemia made the circumstance around len changed,and at last led to the reduce of activities of Na + -K+-ATPase and Ca2+-ATPase in rats' lens epithelial membranes. |
| Keywords: | Hypergalactonemia Na~+-K~+-ATPase Ca~(2+)-ATPase Rat |
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