体表心电图及心外膜标测电恢复性质在诱发猪心室颤动中的作用

目的评价体表心电图及心外膜标测部位电恢复性质在诱发猪心室颤动（室颤）中的作用。方法雄性长白猪7、大，记录心电图的同时用10极单极电极记录心外膜动作电位，构建激动恢复间期（ARI）和QT间期恢复曲线。评价心外膜局部ARI和体表心电图电恢复性质同室颤阈值间的父系。结果局部ARI恢复曲线坡度与QT间期恢复曲线坡度有相关性，差异有统计学意义（r=0．725，P=0．018）。窀颤阈值同右心室心尖部ARI恢复曲线坡度呈正相关（r=0．752，P=0．019），窜颤阈值同体表心电图Ⅱ导联QT间期恢复曲线坡度呈正相关（r＝0．802，P＝0．005）。结论局部ARI及QT间期电恢复性质有明显相关性，两者同室颤诱发相关。

Electrical restitution determined by epicardial contact mapping and surface electrocardiogram: roles in ventricular fibrillation inducibility in swine

Objective The roles of electrical restitution determined by epicardial contact mapping and surface electrocardiogram (ECG) in the inducibility of ventricular fibrillation (VF) were evaluated. Methods Ten epicardial unipolar electrograms using contact mapping and surface ECG were simultaneously recorded in 7 swine. Activation-recovery interval (ARI) and QT interval restitution curves were constructed. Statistical correlations analysis was performed to determine the relationship between local ARI restitutions, QT interval restitution,and ventricular fibrillation threshold. Results One hundred and thirteen restitution curves were constructed (50 in left ventricular sites,52 in right ventricular sites,and 11 in surface ECG lead Ⅱ) from 11 steady-state pacing procedures. Statistical correlation between the slopes of the QT restitution curve and the slopes of regional ARI restitution curves were noted in several mapping sites (r=0.725, P=0.018). Ventricu-lar fibrillation threshold was significantly related to the local ARI restitution curve slope for the right ventricular apex (r=0.752,P=0.019) and the QT-interval restitution curve slope (r=0.802, P=0.005). Conclusion There is a significant correlation between local ARI restitutions and QT-interval restitutions, both of which were associated with VF inducibility.