1周跑台训练对大鼠骨骼肌α-actin基因表达的影响

离心运动可造成骨骼肌损伤，但缺乏对连续离心运动的适应性研究。本研究观察1次（B组）和1周（C组）下坡跑训练对大鼠腓肠肌肌动蛋白基因表达的影响及血清CK、LDH的变化。结果显示1次和1周训练后大鼠腓肠肌肌动蛋白基因表达都出现明显升高，B组大鼠血清CK、LDH运动后7天仍显著高于对照组，C组已恢复正常。结果提示连续离心运动可加速一次离心运动后肌肉损伤的恢复，机体对运动逐渐产生适应。

Effects of Treadmill Training for One Week on α-actin Gene Expression of Rat Skeletal Muscle

It was well known that the damage of skeletal muscle occurred and exercise performance declined after one prolonged eccentric exercise.But there were few studies on the adaptation to the continuous eccentric exercise in skeletal muscle.The purpose of this study was to investigate the effects of downhill running once(group B) and for one week(group C ) on α-actin gene expression of rat gastrocnemius muscle.Serum CK and LDH were determined, too.The results showed that the training had obvious effects on α-actin gene expression of rat gastrocnemius muscle in group B and C.In group B, serum CK and LDH recovered obviously 7 days after training, but not to the normal value.In group C, it recovered to the normal.These results suggest that the recovery of the damage after first training had been accelerated by the continuous eccentric exercise, the subjects gradually adapted to exercise.