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Apport diagnostic des marqueurs biologiques de la maladie d’Alzheimer (MA) dans une observation de dégénérescence lobaire fronto-temporale (DLFT)
Authors:A Richard-Mornas  S Dirson  M Decousus
Institution:a Unité de neuropsychologie-CM2R, CHU de Sainte-Étienne-hôpital Nord, avenue Albert-Raymond, 42055 Saint-Étienne cedex 02, France
b Service de médecine nucléaire, CHU Nord, 42055 Saint-Étienne cedex 02, France
c Service de biochimie, hôpital neurologique Pierre-Wertheimer, 69677 Bron cedex, France
Abstract:

Introduction

Cerebrospinal fluid biomarkers are a fundamental contribution for the diagnosis of Alzheimer disease, in particular for young people.

Case report

We report a case of Alzheimer disease of a 51-years old man whose clinical presentation corresponded to frontotemporal behavioural criteria. The clinical evaluation noticed some troubles in verbal memory. Only the CSF biomarkers confirmed the diagnosis.

Conclusion

There are different phenotypes of presenile Alzheimer disease and among them we note frontotemporal dementia. It is very important to identify them to introduce a specific treatment.
Keywords:MA  DLFT  Biomarqueurs du LCR  Neuropsychologie    mences pré    niles
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