Progressive paraparesis with sensorineural deafness and leukoencephalopathy revealing neurobrucellosis |
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Authors: | Awada A Korri H Issa Z Ali Y Beaini M |
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Institution: | a Service de neurologie, Hôtel-dieu de France, Beyrouth, Liban b Rafik Hariri University Hospital, Beyrouth, Liban c Service de neurochirugie, Hôtel-dieu de France, Beyrouth, Liban |
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Abstract: | IntroductionBrucellosis is a rare disease with variable neurological and imaging manifestations.Case reportA 54-year-old woman presented with progressive paraparesis and sensorineural hearing loss over 18 months. The presence of diffuse white matter changes on brain magnetic resonance imaging (MRI) and cerebrospinal fluid findings led to the diagnosis of neurobrucellosis. Spinal MRI did not show any lesion that could explain the paraparesis that was finally attributed to the leukoencephalopathic lesions. The patient improved clinically after three months of antibiotic treatment but no significant changes were noticed on brain imaging.Discussion and conclusionNeurobrucellosis is a treatable disease which should be discussed when a patient presents with the triade progressive paraparesis, sensorineural hearing loss and leukoencephalopathy on MRI. Outcome can be favorable if adapted treatment is given early. |
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Keywords: | Brucellose Neurobrucellose Leuco-encé phalopathie Mé ningite |
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