Effect of ligands of opiate receptors on morphofunctional state of the sympathoadrenal system and electrical stability of the heart in acute cold exposure |
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Authors: | Yu. B. Lishmanov B. Yu. Kondrat’ev L. N. Maslov N. V. Naryzhnaya |
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Affiliation: | (1) Department of Experimental Cardiology, Institute of Cardiology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk |
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Abstract: | Acute cold exposure (−20°C, 4 h) induces a transient decrease in the ventricular fibrillation threshold without morphological and radionuclide signs of irreversible damage to cardiomyocytes. The agonist of μ-receptors DAGO, which reduces adrenoreactivity of the myocardium, prevents the decrease in the ventricular fibrillation threshold induced by acute cold exposure. Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 123, No. 2, pp. 154–157, February, 1997 |
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Keywords: | ligands ofμ - andδ -receptors cold arrhythmias |
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