Primary breast synovial sarcoma: a rare primary breast neoplasm |
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Authors: | Vicente Tormo Francisco J Andreu |
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Institution: | (1) Department of Human Genetics, University of Utah School of Medicine, 15 North 2030 East, Room 5440, Salt Lake City, UT 84112-5331, USA;(2) Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT, USA;(3) Huntsman Cancer Institute Sarcoma Services, University of Utah, Salt Lake City, UT, USA;(4) Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, UT, USA; |
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Abstract: | A primary synovial sarcoma based on the breast is rare. The usual tumours on the breast are carcinomas. Synovial sarcomas
account for about 6–9% of soft tissue sarcomas and most commonly develop in the extremity of young adults (80%). The other
20% of synovial sarcomas can arise in non-extremity sites (trunk 8%, retroperitoneal/abdominal 7%, head and neck 5%) but synovial
sarcomas can develop in almost any other anatomical location. We report a case of a young woman who presented with a suspected
common breast tumour and started treatment of this tumour with carcinoma neoadjuvant chemotherapy. We were surprised when
the pathologist identified a synovial sarcoma in the histopathology study. |
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