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Primary breast synovial sarcoma: a rare primary breast neoplasm
Authors:Vicente Tormo  Francisco J Andreu
Institution:(1) Department of Human Genetics, University of Utah School of Medicine, 15 North 2030 East, Room 5440, Salt Lake City, UT 84112-5331, USA;(2) Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT, USA;(3) Huntsman Cancer Institute Sarcoma Services, University of Utah, Salt Lake City, UT, USA;(4) Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, UT, USA;
Abstract:A primary synovial sarcoma based on the breast is rare. The usual tumours on the breast are carcinomas. Synovial sarcomas account for about 6–9% of soft tissue sarcomas and most commonly develop in the extremity of young adults (80%). The other 20% of synovial sarcomas can arise in non-extremity sites (trunk 8%, retroperitoneal/abdominal 7%, head and neck 5%) but synovial sarcomas can develop in almost any other anatomical location. We report a case of a young woman who presented with a suspected common breast tumour and started treatment of this tumour with carcinoma neoadjuvant chemotherapy. We were surprised when the pathologist identified a synovial sarcoma in the histopathology study.
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