Monozygote Zwillinge mit Klinefelter-Syndrom (konkordant) und systemischem Lupus erythematodes (diskordant) |
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| Authors: | B. Schlegelberger T. Schlegelberger J. Kekow W. L. Gross W. Grote |
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| Affiliation: | (1) Abteilung Humangenetik im Klinikum der Christian-Albrechts-Universität Kiel, Germany;(2) I. Medizinische Klinik der Christian-Albrechts-Universität Kiel, Germany |
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| Abstract: | Summary Monozygotic twins, both with Klinefelter's syndrome, are presented. One of them had clinical and serological evidence of systemic lupus erythematosus (SLE), whereas the other did not show any immunological disorder. In relation to this case of discordant SLE the role played by exogenous factors in triggering the manifestation of this autoimmune disease under a certain genetic predisposition is discussed.
Abkürzungsverzeichnis KS Klinefelter-Syndrom - SLE Systemischer Lupus erythematodes - CRP C-reaktives Protein - ANA Antinukleäre Antikörper - SK-SD Streptokinase-Streptodornase |
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| Keywords: | Twins Diseases in twins Lupus erythematosus, systemic Klinefelter's syndrome |
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