高频超声探测血管性痴呆患者颈动脉硬化的初步研究

目的探讨血管性痴呆患者检测颈动脉粥样硬化的临床意义。方法经临床确诊的血管性痴呆患者30例，年龄等人口学指标匹配的健康体检者30例作为对照组。利用高频超声探测颈动脉内－中膜厚度（IMT）及粥样硬化斑块形成情况。结果血管性痴呆组的IMT增厚、粥样硬化斑块发生率明显高于对照组（P〈0．05）；血管性痴呆组中软斑检出率高于硬斑及混合斑（P〈0．05）。血管性痴呆组患者的IMT及粥样硬化斑块形成率明显高于对照组，血管性痴呆组检出斑块中软斑占优势。结论高频超声是检测血管性痴呆患者颈动脉粥样硬化的简便而有效的方法，具有重要的临床价值。

Evaluation of carotid atherosclerosis using high-frequency ultrasound in the patients with vascular dementia by

Objective To investigate the clinical significance of high--frequency ultrasound evaluation of carotid atherosclerosis in elderly patients with vascular dementia. Methods Thirty cases with vascular dementia were assigned to vascular dementia group and 30 healthy volunteers to control group which match the vascular dementia group in general clinical data. The high--frequency ultrasound was used to detect the intima--media thickness （IMT） and the atherosclerotie plaque formed within the carotid artery. Results The incidence of carotid atherosclerosis and its plaque formation in vascular dementia group were significantly higher than those in control group. Comparing to that in the control group, the IMT was thicker, the plaques were much more in vascular dementia group （P 〈 0.05） and the character of the plaque was mainly soft in the group of vascular dementia （P 〈 0.05）. The atheroselerotic plaque formation rate in vascular dementia group was significantly higher than that in the control group. Conclusions High--frequency ultrasound is a simple and useful tool in detecting carotid atherosclerosis, therefore possessing important value in assisting clinical diagnosis of vascular dementia.