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Orthotopic Liver Transplantation: Preliminary Analysis of Complications With Grafts From Elderly Donors
Authors:J.R. Naranjo-Izurieta  Z. Ruiz de Azúa-López  J. Lameirao  L. Martín-Villén  A. Roldán-Reina  M. Porras-López  A. Rodríguez-Rodríguez  J.J. Egea-Guerrero
Affiliation:1. Management Unit of Critical Care, University Hospital Virgen del Rocío, Seville, Spain;2. Intrahospital Transplant Coordination, University Hospital Virgen del Rocío, Seville, Spain;3. Sectorial Coordination of Transplants, Sevilla-Huelva, Sevilla, Spain
Abstract:

Objective

This study aims to determine if donor grafts of patients older than 65 years develop more post-transplantation complications than those of younger patients.

Design

This is a retrospective, observational study of liver transplant recipients during 12 months in Virgen del Rocio University Hospital. We compare incidence rates of reperfusion syndrome, acute kidney injury, and need for intra- and postoperative red blood cell transfusions in two donor age groups in which group A is <65 years old and group B is ≥65 years old.

Results

Sixty cases were included. Reperfusion syndrome, acute kidney injury, and both intra- and postoperative red blood cell transfusion were more frequent in group A than group B (11.4% vs. 4%, P = .390; 44% vs. 32%, P = .423; 68.8% vs. 48%, P = .120; and 70.6% vs. 64%, P = .779, respectively). Six recipients (17.1%) died at 12 months from group A whereas there were no deaths register in group B during that time (P = .036).

Conclusion

Our results showed that including elderly donors does not aggravate incidence of complications, emphasizing that advanced age should not be an exclusion criteria for liver transplantation.
Keywords:Address correspondence to José Ricardo Naranjo Izurieta   MD   Management Unit of Critical Care   University Hospital Virgen del Rocío   Avenida Manuel Siurot   s/n   41013 Seville   Spain.
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