二丙酸倍氯米松和干扰素吸入疗法治疗毛细支气管炎的临床研究

目的 研究二丙酸倍氯米松和干扰素吸入疗法治疗毛细支气管炎（毛支）的临床疗效，评价其临床价值。方法 将83例毛支患儿随机分为两组，两组病例采用相同的综合治疗，治疗组（n=42）在综合治疗基础上，急性期行干扰素吸入治疗及缓解期行二丙酸倍氯米松长期吸入治疗，对治疗前后主要症状及体征的持续时间，平均住院天数进行比较。结果 急性期在治愈率、喘憋缓解、肺部哮鸣音及湿哕音消失时间及住院时间等方面，治疗组明显优于对照组（P〈0．01）。恢复期治疗组喘息率低于对照组。结论 急性期吸入干扰素有利于疾病的恢复，恢复期吸入二丙酸倍氯米松可减少喘息的发作。

Effect of inhalation therapy of beclometasone and interferon for the treatment of bronchiolitis in children

Objective To explore effects of the beclomethasone-interferon inhalation therapy on bronchiolitis.Methods Eighty-three children with bronchiolitis were randomly divided into therapy group(n=42) and control group(n=41).The control group was given routine treatment,and additionally,the therapygroup received inhalation therapy of beclometasone and interferon.The symptom/sign duration and average hospital stay time were compared between the two groups.Results During the acute stage,treatment group showed higher cure rate,more obvious asthma relief,less wheezing/wet rales and shorter hospital stay than control group(P<0.01).Asthma incidence at recovery stage was lower in therapy group as compared with control.Conclusion Interferon inhalation can improve the recovery of bronchiolitis at acute stage and beclometasone inhalation can reduce the asthma attack during recovery stage.