连续性肾脏替代治疗在多脏器功能障碍患者中的临床疗效

目的探讨连续性肾脏替代疗法(CRRT)在多脏器功能障碍(MODS)患者中的临床疗效。方法回顾性研究我院2009年10月～2012年6月接受CRRT治疗的MODS患者的临床资料,其39例,162例次,通过分析比较其开始CRRT治疗时间,治疗次数及治疗前后血生化、血常规及生命体征变化,探讨CRRT在MODS患者中的临床疗效。结果所有入选患者治疗期间生命体征平稳,治疗后血尿素氮(BUN)、血肌酐(SCr)较前均明显下降(P均<0.05);血白细胞、中性粒细胞百分比均明显下降(P均<0.05)。结论 CRRT能显著改善MODS患者的临床症状,增加其抢救成功率,临床疗效确切,为抢救MODS患者的有效手段。

Effect of treatment by continuous renal replacement therapy in patients with multiple organ dysfunction syndrome

Objective To discuss the clinical effect of continuous renal replacement treatment （CRRT） in patients with multiple organ dysfunction syndrome（MODS）. Methods Reviewing 39 cases with MODS were treated by CRRT in our hospital from 2009 October to 2012 June,by the analysis and comparison of the CRRT treatment time,treatment times, blood routine, blood biochemical and vital signs before and after treatment to discuss the effect of treatment by CRRT in patients with MODS. Results All patients with stable vital signs during treatment.The levels of blood urea nitrogen （BUN）, serum creatinine （Cr）, blood white cells （WBC） and the neuter granulocyte percentage were significantly decreased after treatment （P 〈 0.05）. Conclusion CRRT could significantly improve the clinical symptoms of the MODS patients, increase the success rate of rescue,clinical curative effect is accurate,and is an clinical effective therapeutic option for patients with multiple organ dysfunction syndrome.