| 丝裂霉素C术中应用对膀胱癌术后复发部位的影响 |
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| 引用本文： | 章宗武,梁朝朝.丝裂霉素C术中应用对膀胱癌术后复发部位的影响[J].安徽卫生职业技术学院学报,2008,7(2):36-38. |
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| 作者姓名： | 章宗武 梁朝朝 |
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| 作者单位： | 1. 安徽省立新安医院泌尿外科,合肥,230022
2. 安徽医科大学第一附属医院泌尿外科,合肥,230022 |
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| 摘 要： | 目的：探讨低剂量丝裂霉素C（MMC）术中肿瘤基底部注射联合即刻膀胱灌注或联合膀胱粘膜下注射对膀胱癌（BC）术后复发部位变化及其治疗方式的影响。方法：73例膀胱移行细胞癌初发病例，均接受保留膀胱手术。术中随机分成三组：A组采用低剂量MMC（10mg，0．10/l）术中肿瘤基底部注射联合膀胱即刻灌注27例，B组采用相同剂量的MMC术中肿瘤基底部注射联舍膀胱粘膜下注射22例。C组24例仅MMC（（0．40g／1））术后定期膀胱灌注治疗。术后随访12-60个月。结果：A组原位复发1例，异位复发2例。复发率（RR）11．11％。B组原住和异住复发各1例，RR9．09％。C组原位复发8例，RR为37．50％。治疗期间，有39例发生局部反应，未见膀胱粘膜坏死、骨髓抑制等严重并发症。结论：低剂量MMC术中肿瘤基底部注射联合即刻膀胱灌注或联合膀胱粘膜下注射，其疗效均明显优于单纯MMC术后定期膀胱灌注治疗。
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| 关 键 词： | 膀胱癌 丝裂霉素C 粘膜注射 灌注 |
| 文章编号： | 1671-8054(2008)02-0036-03 |
| 修稿时间： | 2008年1月19日 |
Influence on the postoperative recurrence site in bladder cancer treated with Mitomycin C during Surgery |
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| ZHANG Zong-wu,LIANG Chao-zhao.Influence on the postoperative recurrence site in bladder cancer treated with Mitomycin C during Surgery[J].Journal of Anhui Heaith Vocational & Technical College,2008,7(2):36-38. |
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| Authors: | ZHANG Zong-wu LIANG Chao-zhao |
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| Institution: | ZHANG Zong-wu,LIANG Chao-zhao Department of Urology,Anhui Provincial Xin\'an Hospital,Hefei 230022,Anhui |
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| Abstract: | Objective To discuss influence of injecting into the tumour base plus perfusing inside bladder instantly or injecting bladder mucous membrane during surgery on the postoperative recurrence site and treatments of bladder cancer (BC)by low dose Mitomycin C(MMC). Methods A total of 73 cases which had initial transitional cell cancer were treated with bladder-sparing surgery. These cases were divided randomly into 3 groups: 27 cases in Group A were treated with injecting into the tumour base and perfusing insid... |
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| Keywords: | Bladder neoplasms Mitomycin C Submucous injection Perfusion |
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