| 香菇多糖注射液对慢性乙型肝炎外周血单个核细胞膜IL—2受体表达的影响 |
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| 引用本文： | 万克青. 香菇多糖注射液对慢性乙型肝炎外周血单个核细胞膜IL—2受体表达的影响[J]. 湖南医科大学学报, 1998, 23(1): 90-92 |
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| 作者姓名： | 万克青 |
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| 摘 要： |
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| 关 键 词： | 香菇多糖 白细胞介素2 受体 乙型肝炎 |
Effects of lentinan of peripheral blood mononuclear cell expression of interleukin-2 receptor in patients with chronic hepatitis B in vivo and in vitro] |
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| K Wan. Effects of lentinan of peripheral blood mononuclear cell expression of interleukin-2 receptor in patients with chronic hepatitis B in vivo and in vitro][J]. Bulletin of Hunan Medical University, 1998, 23(1): 90-92 |
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| Authors: | K Wan |
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| Affiliation: | Department of Infectious Diseases, Third Affiliated Hospital, Hunan Medical University, Changsha. |
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| Abstract: | The effects of lentinan on peripheral blood mononuclear cell (PBMC) expression of IL-2 receptor in patients with chronic hepatitis B in vitro and in vivo were studied. The expression percentage of IL-2 receptor in 44 patients with chronic hepatitis before treatment was 36.74 +/- 7.74, which was lower than healthy subjects, and was 48.92 +/- 3.79 after 2 months treatment of lentinan, which was approximated the normal control. PBMC from 30 patients with chronic hepatitis B were cultured in vitro with or without lentinan. The percentage of expression IL-2 receptor was 12.81 +/- 2.62 without lentinan and was 35.70 +/- 4.87 in the presence of lentinan. The concentration of lentinan stimulating expression of IL-2 receptor was between 0.2 to 200 g.ml-1. The results suggest that lentinan stimulates expression of IL-2 receptor on PBMC, which is associated with the therapeutic effectiveness of lentinan treatment. |
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