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BP神经网络结合遗传算法用于丹参提取工艺的多目标优化
引用本文:杨铭,汪文娟. BP神经网络结合遗传算法用于丹参提取工艺的多目标优化[J]. 药学服务与研究, 2007, 7(6): 417-421
作者姓名:杨铭  汪文娟
作者单位:1. 上海中医药大学附属龙华医院药剂科,上海,200032
2. 上海中医药大学中药学院中药教研室,上海,201203
摘    要:目的:使用BP神经网络结合遗传算法用于丹参提取工艺的多目标优化。方法:通过已知文献的丹参提取工艺优化实例,采用均匀设计法优化BP神经网络模型参数,并建立网络模型,再利用遗传算法对网络进行多目标寻优,获得丹参最佳提取工艺。结果:BP神经网络结合遗传算法用于丹参提取工艺的多目标优化,模型拟合度和预测性均高于文献采用的多元回归法。结论:BP神经网络结合遗传算法可用于丹参提取工艺的多目标优化。

关 键 词:丹参  提取法  神经网络(计算机)  遗传算法  多目标优化
文章编号:1671-2838(2007)06-0417-05
收稿时间:2007-04-30
修稿时间:2007-11-08

Back-propagation neural network and genetic algorithm for multi-objective optimization of extraction technology of Salvia miltiorrhiza Bge.
YANG Ming,WANG Wen-juan. Back-propagation neural network and genetic algorithm for multi-objective optimization of extraction technology of Salvia miltiorrhiza Bge.[J]. Pharmaceutical Care and Research, 2007, 7(6): 417-421
Authors:YANG Ming  WANG Wen-juan
Abstract:Objective: To introduce back-propagation(BP) neural network and genetic algorithm for multi-objective optimization of extraction technology of Salvia miltiorrhiza Bge..Methods: BP neural network was established and optimized with uniform design method based on the data in literature of optimization of extraction process of Salvia miltiorrhiza Bge.Genetic algorithm was used for multi-objective optimization to obtain optimal extraction technology of Salvia miltiorrhiza Bge..Results:With BP neural network and genetic algorithm for multi-objective optimization of extraction technology of Salvia miltiorrhiza Bge.,the fitting and prediction were better than those of the multiple regression reported in literature.Conclusion: BP neural network and genetic algorithm for multi-objective optimization of extraction technology of Salvia miltiorrhiza Bge.is advisable.
Keywords:Salvia miltiorrhiza  extraction  neural network(computer)  genetic algorithm  multi-objective optimization
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