脉络宁注射液致过敏性休克46例文献分析

目的:探讨脉络宁注射液致过敏性休克的特点和规律,为临床安全合理用药提供参考。方法:检索中国知网全文数据库(CNKI)1990-2011年中脉络宁注射液致过敏性休克的文献资料,并进行归纳分析。结果:发生过敏性休克的46例患者中有45例为首次用药。10min内发生休克的38例,占82.60%;39例于5min～12h内缓解或痊愈,有1例死亡,其他未提及好转时间。结论:临床应重视脉络宁注射液致过敏性休克,加强10min内用药监测,以确保用药安全。

Literature Analysis of 46 Cases Anaphylactic Shock Induced by Mailuoning Injection

OBJECTIVE:To explore the characteristics and regulation of anaphylactic shock induced by Mailuoning injection, and to provide reference for rational drug use in the clinic. METHODS: Anaphylactic shock cases induced by Mailnoning injection reported in CNKI from 1990-2011 were retrieved and analyzed statistically. RESULTS: There were totally 46 patients, who suffered anaphylactic shock. Anaphylactic shock occurred right after first medication for 45 patients. For 38 patients, it occurred in 10 minutes, corresponding to 82.60%, and symptom was relieved or patients were fully recovered between 5 minutes and 12 hours for 39 cases. Unfortunately, there was one death. For the other patients, recovery time was not mentioned. CONCLUSIONS: Great importance should be attached to anaphylactic shock caused by Mailnoning injection, and monitoring 10 minutes after injection should be enhanced to ensure the security of medication.