| 药用植物提取物20种抗幽门螺杆菌的活性研究 |
| |
| 引用本文： | 韩艳,张琰,刘新友,覃华,杜晓燕,杨艳红.药用植物提取物20种抗幽门螺杆菌的活性研究[J].西北国防医学杂志,2011,32(6):413-415. |
| |
| 作者姓名： | 韩艳 张琰 刘新友 覃华 杜晓燕 杨艳红 |
| |
| 作者单位： | 1. 第四军医大学唐都医院,药剂科,陕西西安710038
2. 第四军医大学唐都医院,妇产科,陕西西安710038 |
| |
| 基金项目： | 陕西省自然科学基金资助项目(SJ08C211) |
| |
| 摘 要： | 目的:对20种药用植物的抗幽门螺杆菌活性进行初步筛选.方法:分别提取20种药用植物的醇溶性和水溶性部位,采用琼脂稀释法,以氨苄西林为对照,体外法测定样品对幽门螺旋杆菌菌株的最小抑菌浓度.结果:苍耳子、鹅不食草、蒲公英、菊花、佩兰、艾叶的醇提物无抑菌活性；青木香、鹅不食草、紫苑、菊花、茵陈、佩兰、艾叶、乌药、黄芪的水提物无抑菌活性；丁香和云木香醇提物的MIC为40 μg/ml.结论:丁香和云木香乙醇提取物显示了较强的抗幽门螺杆菌活性,为进一步确定抗幽门螺旋杆菌的有效成分和寻找先导化合物奠定了良好基础.
|
| 关 键 词： | 药用植物 提取物 幽门螺杆菌 最小抑菌浓度 |
Helicobacter pylori eradication with extractive of 20 species of medicinal plants |
| |
| HAN Yan,ZHANG Yan,LIU Xin-you,et al..Helicobacter pylori eradication with extractive of 20 species of medicinal plants[J].Medical Journal of National Defending Forces in Northwest China,2011,32(6):413-415. |
| |
| Authors: | HAN Yan ZHANG Yan LIU Xin-you |
| |
| Institution: | HAN Yan,ZHANG Yan,LIU Xin-you,et al.(Department of Pharmacy,Tangdu Hospital,Fourth Military Medical University,Xi'an 710038,China) |
| |
| Abstract: | Objective:To extract the active compound against the helicobacter pylori with 20 species of medicinal plants.Methods:The ethanol-soluble and water-soluble fractions of the 20 species of medicinal plants were obtained.MIC against helicobacter pylori were determined in vitro with ampicillin as compared drug by the method of agar dilution.Results:The ethanol-soluble and water-soluble fractions of some species of medicinal plants have good anti-helicobacter pylori action,but there were differences compared with... |
| |
| Keywords: | Medicinal plants Extractions Helicobacter pylori MIC |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
