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茵陈蒿汤分煎、合煎对利胆及腹腔巨噬细胞吞噬功能影响的比较研究
引用本文:李兰芳,金亚宏,原桂东,阴赪宏,曹秀芳,姜廷良,周嘉琳,王永山.茵陈蒿汤分煎、合煎对利胆及腹腔巨噬细胞吞噬功能影响的比较研究[J].中国实验方剂学杂志,1998,4(4):39-41.
作者姓名:李兰芳  金亚宏  原桂东  阴赪宏  曹秀芳  姜廷良  周嘉琳  王永山
作者单位:中国中医研究院中药研究所,江苏天江制药有限公司
摘    要:大鼠经十二指肠分别给予茵陈蒿汤分煎、合煎药液,观察药后0.5、1、2、3、4h的胆汁排出量,实验结果表明,茵陈蒿汤分煎、合煎的14.85g/kg剂量组能明显增加大鼠胆汁排出量。以茵陈蒿汤分煎、合煎药液对泼尼松造型的小鼠分别灌胃7d,能显著提高其腹腔巨噬细胞的吞噬率和吞噬指数。在两种药效学指标上,茵陈蒿汤分煎、合煎无显著性差异

关 键 词:茵陈蒿汤  分煎  合煎  利胆  吞噬功能
收稿时间:3/9/1998 12:00:00 AM

Comparative Study of Separate and Mixed Yinchenhao Decoctions on Choleretic Effects and Phagocytic Function of Celiac Macrophage
Li Lanfang,Jin Yahong,Yuan Guidong,Yin Chenghong,Cao Xiufang,Jiang Tingliang;Zhou Jialin,Wang Yongshan.Comparative Study of Separate and Mixed Yinchenhao Decoctions on Choleretic Effects and Phagocytic Function of Celiac Macrophage[J].China Journal of Experimental Traditional Medical Formulae,1998,4(4):39-41.
Authors:Li Lanfang  Jin Yahong  Yuan Guidong  Yin Chenghong  Cao Xiufang  Jiang Tingliang;Zhou Jialin  Wang Yongshan
Institution:1Institute of Chinese Materia Medica,China Academy of TCM,Beijing,100700;2Jiangsu Tianjiang Pharmaceutical Co.Ltd,Jiangyin,214433
Abstract:The bile output in rats was investigated at 0.5,1,2,3,4 hour after the separate and the mixed Yinchenhao decoctions were respectively administrated by duodenum.It was showed that both decoctions (14 85g/Kg)could significantly increase the bile output in rats compared with control group.Three dosages of each decoction could obviously increase phagocytic rate and index of celiac macrophage in pathologic model mice induced by prednisone after two decoctions had been administrated for 7 days,as compared with model group.The results indicated that there was no marked difference in two pharmacodynamics of choleretic effect and phagocytic function possessed by separate and mixed Yinchenhao decoctions. \ \
Keywords:Yinchenhao decoction  separate decoction  mixed decoction  choleretic effect  phagocytic function
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