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Cellular junctions in normal and inflammatory human synovial membrane revealed by tannic acid and freeze fracture
Authors:Antoine Dryll  Juliette Lansaman  André Paul Peltier  Antoine Ryckewaert
Affiliation:(1) Laboratoire de Microscopie Electronique, Clinique Rhumatologique, Unité INSERM U18, Hôpital Lariboisière, 6 Rue Guy Patin, F-75010 Paris, France
Abstract:Summary Cellular junctions between synovial cells and endothelial cells of the microvasculature were examined in 10 normal and 20 inflammatory human synovial membranes by means of tannic acid and freeze fracture, Gap junctions and desmosomes predominated on synovial cells, and tight junctions in the microvasculature.Comparison between normal and inflammatory synovial membranes did not demonstrate changes in cellular contacts that might be caused by inflammation.
Keywords:Human synovial membrane  Cellular junctions  Tannic acid  Freeze fracture
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