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| 人乳头瘤状病毒在头颈部鳞状细胞癌中的研究进展 | |
| 引用本文： | 崔广学,高晓磊,梁新华. 人乳头瘤状病毒在头颈部鳞状细胞癌中的研究进展[J]. 华西口腔医学杂志, 2017, 35(2): 187-191. DOI: 10.7518/hxkq.2017.02.015 |
| 作者姓名： | 崔广学 高晓磊 梁新华 |
| 作者单位： | 1.赤峰学院附属医院口腔颌面外科,赤峰 024000 2.口腔疾病研究国家重点实验室,国家口腔疾病临床研究中心,四川大学华西口腔医院口腔颌面外科,成都 610041 |
| 基金项目： | The National Natural Science Foundation of China (81361120399). 国家自然科学基金 |
| 摘 要： | 高危型人乳头瘤状病毒是宫颈癌的主要致病因素,近年来研究发现人乳头瘤状病毒感染与头颈部鳞状细胞癌的发生也存在密切关系。本文对人乳头瘤状病毒相关性头颈部鳞状细胞癌的流行病学、致癌机制、诊断方法、治疗及预后等方面的研究进展作一综述。 |
| 关 键 词： | 人乳头瘤状病毒 头颈部鳞状细胞癌 致癌基因 |
| 收稿时间： | 2016-05-15 |
| 修稿时间： | 2016-08-10 |
Role of human papillomavirus in head and neck squamous cell carcinomas |
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| Cui Guangxue,Gao Xiaolei,Liang Xinhua. Role of human papillomavirus in head and neck squamous cell carcinomas[J]. West China journal of stomatology, 2017, 35(2): 187-191. DOI: 10.7518/hxkq.2017.02.015 | |
| Authors: | Cui Guangxue Gao Xiaolei Liang Xinhua |
| Affiliation: | 1. Dept. of Oral and Maxillofacial Surgery, Affiliated Hospital of Chifeng University, Chifeng 024000, China 2. State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Dept. of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China |
| Abstract: | Human papillomavirus (HPV) is a major causative agent of cervical cancers. Over the past several decades, increasing number of studies established strong association of HPV with a subset of head and neck squamous cell carcinomas (HNSCCs). In the present study, we reviewed evidence, including epidemiology, carcinogens, diagnosis, treatment, and pro-gnosis, showing that HPV-positive HNSCCs exhibit a variety of distinct characteristics for understanding tumor biology and improving cancer treatment. |
| Keywords: | human papillomavirus head and neck squamous cell carcinomas carcinogene |
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