根管冲洗剂QMix冲洗性能的研究进展

根管预备时,采用单纯机械预备方法无法完全去除根管内感染,化学冲洗是消除根管内感染不可或缺的步骤。理想的根管冲洗剂应具备彻底清除玷污层、润滑根管、有效杀菌、对组织无毒性且不损伤牙齿结构的特点。现有的根管冲洗剂尚不能同时满足上述所有要求。QMix是由乙二胺四乙酸（EDTA）、氯己定（CHX）和表面活性剂混合组成的根管冲洗剂。QMix能够有效去除玷污层,杀菌性强且有持续的抗菌作用,细胞毒性小且生物相容性好,对牙本质的着色浅,对牙本质微硬度的影响小。此外,QMix还可以提高根管封闭剂的润湿性且不影响其粘接性能。本文比较QMix与其他常用的根管冲洗剂（如次氯酸钠、CHX、EDTA、SmearClear、MTAD等）在去除玷污层、对牙本质作用、对根管封闭剂的影响、细胞毒性、抗菌作用等方面的作用特点,将目前对QMix的研究成果作一综述。

Research progress on QMix properties in root canal irrigation

Mechanical instrumentation preparation alone is insufficient to completely remove root canal infection, and chemical irrigation is essential to eliminate infected remnants. An ideal root canal irrigant should completely remove the smear layer, lubricate the root canal, efficiently kill bacteria, induce mild or no inflammatory response in the tissues, and avoid damaging the dentin structure. However, a commercial irrigant that meets all these requirements is currently lacking. QMix is a root canal irrigation mixture of ethylenediamine tetraacetic acid (EDTA), chlorhexidine (CHX) and surfactant. This mixture can remove the smear layer efficiently, and it possesses strong antibacterial effect and good biocompatibility with minimal cytotoxicity. Furthermore, the influence of QMix on the color and micro-hardness of dentin is low, and it can improve the wettability of root canal sealant without affecting its adhesive properties. This review compares the efficiencies of QMix with other irrigants (sodium hypochlorite, CHX, EDTA, SmearClear, and MTAD) in term of smear layer removal, dentine and root canal sealing, cell cytotoxicity, and bacterial growth inhibition.