STD患者血清抗TTV IgG及性传播途径研究

目的：探讨输血传播病毒（TTV）在STD患者中的感染状况及经性传播的可能性。方法：应用ELISA法检测237例STD患者和80例健康体检正常人的血清抗TTV IgG。结果：STD患者抗TTV IgG的阳性率明显高于正常人群（P＜0．005）；不同STD病种患者中以梅毒、生殖器疱疹以及梅毒合并NGU和CA、生殖器疱疹合并NGU的患者的抗TTV IgG的阳性率较高，而非淋菌性尿道炎患者的抗TTV IgG阳性率较低；STD患者男性与女性抗TTV IgG的阳性率两者无显著性差异（P＞0．05）；STD患者配偶抗TTV IgG阳性率为30．36％，正常人配偶抗TTV IgG的阳性率为4．55％，两者存在显著性差异（P＜0．05）；抗TTV IgG阳性组和抗TTV IgG阴性组的STD患者冶游史大于半年以上者的人数分别为23，7（P＜0．005），性伴侣平均个数分别16．80，7．53（P＜0．001）。结论：STD患者中存在严重的TTV感染；冶游史的时间越长，性伴侣个数越多感染TTV可能性越大，提示性传播可能是TTV感染途径之一。

Study on serological TTV IgG and TTV sexual transmission route in STD patients

Objective To study transfusion transmitted virus(TTV) infection and the possibility of the sexual transmission in STD patients.Methods Anti-TTV IgG was tested by ELISA in the serum of 237 cases of STD patients and 80 cases of normal married adults.Results Anti-TTV IgG positive rate was much higher in STD patients than in normal married adults(P<0 005).The higher positive rates in different STD diseases were syphilis,genital herpes,syphilis amalgamating NGU,syphils amalgamating CA,genital herpes amalgamating NGU.The lower positive rate was NGU.There was no significance between the positive rate of anti TTV IgG of male STD patients and that of female STD patients(P>0 05).There was noticeable significance(P<0 05).The positive rate of anti-TTV IG of patient's spouses was 30.36%,that of normal people's spouses ws 4.55%.Twenty three cases in anti-TTV IgG positive STD group and 7 cases in anti-TTV IgG negative STD group had over six months of frequent brothels history(P<0 005).The average number of sexual intercourse mates was 16.80 in anti-TTV IgG positive STD group and 7.53 in anti-TTV IgG negative STD group(P<0 01).Conclusion There was a relatively high TTV infection rate in STD patients.The more time of frequent brothels history and the more numbers of different sexual intercourse mates patients had,the more possibility STD patients were infected TTV.This indicated that sexual transmission might be another infectious route of TTV.