| 手足口病病原学和流行病学研究进展 |
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| 引用本文： | 张静,李秀惠,李丽,尚小飞. 手足口病病原学和流行病学研究进展[J]. 中华流行病学杂志, 2022, 43(5): 771-783 |
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| 作者姓名： | 张静 李秀惠 李丽 尚小飞 |
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| 作者单位： | 中国疾病预防控制中心传染病管理处;首都医科大学附属北京佑安医院中西医结合中心 |
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| 基金项目： | 国家科技重大专项(2017ZX10305501004)； |
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| 摘 要： | 手足口病是世界范围广泛流行的传染病，多发生于5岁以下儿童，可引起手、足、口腔等部位的皮疹和疱疹，部分重症可导致死亡，严重威胁儿童健康。肠道病毒A组71型（EV-A71）和柯萨奇病毒A组16型（CV-A16）等EV是引起我国手足口病持续流行的主要病因。2013年以后，其他EV在手足口病病例中所占比例逐渐增多，引起重症和死...
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| 关 键 词： | 手足口病 流行病学 病原学 肠道病毒 |
| 收稿时间： | 2021-10-12 |
Etiology and epidemiology of hand, foot and mouth disease in China |
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| Zhang Jing,Li Xiuhui,Li Li,Shang Xiaofei. Etiology and epidemiology of hand, foot and mouth disease in China[J]. Chinese Journal of Epidemiology, 2022, 43(5): 771-783 |
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| Authors: | Zhang Jing Li Xiuhui Li Li Shang Xiaofei |
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| Affiliation: | Division of Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China;Integrated Traditional Chinese and Western Medicine Center, Beijing Youan Hospital of Capital Medical University, Beijing 100069, China |
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| Abstract: | Hand, foot and mouth disease (HFMD) has been widespread in the world, and caused fever, rashes and other clinical symptoms of children, and sometimes inducing respiratory failure, brainstem encephalitis, and other complications, even death. The disease is mainly caused by enterovirus 71 (EV-A71) and coxsackievirus 16 (CV-A16). Since 2013, the proportion of HFMD cases caused by other enteroriruses has gradually increased, causing severe and even fatal cases. This paper summarizes the research progress in the epidemiological and etiological characteristics of HFMD in China since 2008. |
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| Keywords: | Hand, foot, and mouth disease Epidemiology Etiology Enterovirus |
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