全口义齿垂直距离恢复过低对脑血流的影响

目的研究全口义齿垂直距离恢复过低对脑血流的影响。方法选取10例无牙颌患者,应用经颅多普勒超声诊断仪,探测全口义齿垂直距离恢复过低患者（降低5 mm）在咀嚼前、咀嚼10 min和咀嚼20 min时大脑中动脉的平均峰流速度、收缩期峰流速度和舒张期末峰流速度。试验采取自身前、后对照,应用SPSS18.0软件包对数据进行独立样本t检验和方差分析。结果试验组在咀嚼前、咀嚼10 min和咀嚼20 min时的血流速度无显著变化,而对照组血流速度显著升高。试验组在咀嚼10 min后血流速度显著性低于对照组,咀嚼20 min后血流速度无显著变化。结论全口义齿垂直距离恢复过低患者在咀嚼运动时脑血流无显著增加。

The influence of lower vertical dimension construction of complete denture on cerebral blood flow

PURPOSE: To investigate the influence of lower vertical dimension construction on cerebral blood flow among patients with complete denture. METHODS: Ten edentulous patients were chosen and lower vertical dimension was constructed with complete denture. Transcranial Doppler ultrasonography was used to detect the average peak flow velocity, peak systolic velocity and end-diastolic peak flow velocity of the middle cerebral artery. The detection was performed before chewing, 10 minutes after chewing and 20 minutes after chewing, respectively. Before-after self control study was designed, and SPSS18.0 software package was used to analyze the data with independent samples t test and multiple comparisons and analysis of variance. RESULTS: There was no significant increase in cerebral blood flow before chewing, 10 minutes after chewing and 20 minutes after chewing in the experimental group, while blood flow velocity of the control group was significantly increased. The blood flow velocity of the experimental group 10 minutes after chewing was significantly lower than that of the control group, while no significant difference was found after chewing between the experimental group and control group 20 minutes. CONCLUSIONS: No significant increase of cerebral blood flow is detected in patients whose vertical dimension are lower when restored with complete denture during mastication.