Toxic effects of certain pentacyclic triterpenoids on early embryogenesis of the sea urchin. |
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| Authors: | M M Anisimov E B Shentsova V V Shcheglov L I Strigina N S Chetyrina N G Aladjina |
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| Affiliation: | Pacific Institute of Bio-organic Chemistry, Far East Science Centre, U.S.S.R. Academy of Sciences, Vladivostok-22, U.S.S.R.;All-Union Research Institute for Medicinal Plants, Moscow, U.S.S.R.;Leningrad University, Leningrad, U.S.S.R. |
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| Abstract: | The cytotoxic activity on the developing sea urchin embryos of forty-four pentacyclic triterpenes of plant origin has been studied. Pentacyclic triterpene glycosides from oleanolic acid and hederagenin with free carboxyl groups at C-28 had the highest cytotoxic activity. Triterpenes from meristotropic acid, macedonic acid and lupan did not display cytotoxic effects. |
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