|
|||||
|
|
| 番茄红素对镉中毒大鼠体内抗氧化酶活力影响 | |
| 引用本文： | 潘洪志,万丽葵,孙胜波,王德才,那立欣. 番茄红素对镉中毒大鼠体内抗氧化酶活力影响[J]. 中国公共卫生, 2004, 20(12): 1477-1478 |
| 作者姓名： | 潘洪志 万丽葵 孙胜波 王德才 那立欣 |
| 作者单位： | 1. 哈尔滨医科大学公共卫生学院,哈尔滨,150001 2. 黑龙江省疾病预防控制中心 3. 黑龙江省出入境检验检疫局 |
| 摘 要： | 目的 观察番茄红素 (lycopene,LP)对镉 (Cd)中毒大鼠抗氧化酶系统的影响。 方法 大鼠饲喂CdCl2 和番茄红素 ,4周后处死 ,测定血清和肝匀浆的超氧化物歧化酶 (SOD)活性、过氧化氢酶 (CAT)活性、谷胱甘肽过氧化物酶 (GSH -Px)活力、丙二醛 (MDA)及还原型谷胱甘肽 (GSH)含量。结果 与模型组相比 ,番茄红素组的大鼠血清和肝组织的SOD活性、GSH -Px活力上升 ,MDA含量降低 ,有显著性差异 (P <0 0 5 )。结论 番茄红素可以拮抗镉的毒性 ,提高大鼠机体的抗氧化能力 ,抑制镉中毒所致的脂质过氧化。 |
| 关 键 词： | 番茄红素 镉 抗氧化 |
| 文章编号： | 1001-0580(2004)12-1477-02 |
| 修稿时间： | 2004-04-19 |
Effect of lycopene on antioxidative enzyme in rats induced by Cd |
|
| PAN Hong-zhi,WAN Li-kui,SUN Sheng-bo,et al.. Effect of lycopene on antioxidative enzyme in rats induced by Cd[J]. Chinese Journal of Public Health, 2004, 20(12): 1477-1478 | |
| Authors: | PAN Hong-zhi WAN Li-kui SUN Sheng-bo et al. |
| Affiliation: | PAN Hong-zhi,WAN Li-kui,SUN Sheng-bo,et al.Public Health School of H arbin Medical University |
| Abstract: | Objective To observe the effect of Lycopene(LP) on antiox idation in rats induced by Cd. Methods The rats were given Cd and LP.After 4 weeks the a ctivity of SOD,MDA and GSH-Px,GSH,CAT in serum and liver were measured respectiv ely.Results The activities of antioxidative enzymes in model group were reduced.Compared with model group,the activities of SOD and GSH-Px in LP group were increased and the concentrations of MDA were decreased significan tly(P<0.05). Conclusion LP could increase antioxidative effect and red uce lipid peroxidation in Wistar rats induced by Cd. |
| Keywords: | lycopene Cd antioxidation |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |