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| 幽门螺杆菌感染后胃窦部内分泌细胞变化的电镜观察 | |
| 引用本文： | 何燕萍,宋于刚,刘连璞,朴英杰,何美蓉.幽门螺杆菌感染后胃窦部内分泌细胞变化的电镜观察[J].南方医科大学学报,2002,22(3):239-240，246. |
| 作者姓名： | 何燕萍 宋于刚 刘连璞 朴英杰 何美蓉 |
| 作者单位： | 1. 第一军医大学南方医院全军消化内科研究所,广东广州,510515 2. 第一军医大学电镜室,广东广州,510515 3. 第一军医大学解剖教研室,广东广州,510515 |
| 基金项目： | 广东省重点科技攻关课题(粤科计字-99-245-13号) |
| 摘 要： | 目的研究幽门螺杆菌感染后胃窦部内分泌细胞的超微结构变化。方法将经快速尿素酶试验及组织化学染色(甲苯胺蓝法)检查确诊为Hp阳性的慢性胃窦炎患者5人作为试验组,Hp阴性的慢性胃炎患者2人作为对照组,用透射电镜观察胃窦部内分泌细胞变化。结果透射电镜观察结果显示Hp阳性患者内分泌细胞内分泌颗粒电子密度增加,壁细胞分泌状态活跃。结论Hp感染后内分泌细胞变化可解释Hp感染后相应激素变化。 |
| 关 键 词： | 螺杆菌属 内分泌细胞 显微镜检查 电子 |
| 文章编号： | 1000-2588(2002)03-0239-02 |
| 修稿时间： | 2001年11月28 |
Electron microscopic observation of endocrine cells in the antrum in response to Helicobacter pylori infection |
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| HEYan-ping ,SONGYu-gang ,LIULian-pu ,PIAOYing-jie ,HEMei-rong Institutefor DigestiveDiseasesof PLA,NanfangHospital ,Depatmentof ElectronMicroscopy ,.Electron microscopic observation of endocrine cells in the antrum in response to Helicobacter pylori infection[J].Journal of Southern Medical University,2002,22(3):239-240，246. | |
| Authors: | HEYan-ping SONGYu-gang LIULian-pu PIAOYing-jie HEMei-rong Institutefor DigestiveDiseasesof PLA NanfangHospital Depatmentof ElectronMicroscopy |
| Institution: | HEYan-ping 1,SONGYu-gang 1,LIULian-pu 2,PIAOYing-jie 3,HEMei-rong 1 Institutefor DigestiveDiseasesof PLA,NanfangHospital 1,Depatmentof ElectronMicroscopy 2,Departmentof Anatomy 3,FirstMilitaryMedicalU |
| Abstract: | Objective To observethe ultrastructuralchangesof the endocrinecellsin the antrumafterthe onsetof Helicobacter pylori(Hp)infection.Methods Sevenpatientswithchronicgastritiswereincludedin thisstudy,andtoluidine bluestainingandrapidureasetestwereperformedto determinetheHp statusof thegastricantralmucosabiopsies.Five patientsidentifiedas beingpositivefor Hpconstitutedthetestgroup,leavingthe2Hp-negativepatientsservingas control.Theendocrinecellsintheantrumof thepatientsweresampledto observetheultrastructuralchangesby transmissionelectron microscopy(TEM).Results TEMshowedincreasedelectrondensityof thesecretiongranulesintheendocrinecells,and secretionsintheparietalcellswereactive.Conclusion Theultrastructuralchangesof theendocrinecellsintheantrummight explainhighgastrinlevelsaftertheonsetof Hpinfection. |
| Keywords: | Helicobacter pypori endocrinecells microscopy electron |
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