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胞磷胆碱治疗脑血栓形成病人57例
引用本文:聂成福,张文田,李松奎,张传文. 胞磷胆碱治疗脑血栓形成病人57例[J]. 中国新药与临床杂志, 1989, 0(4)
作者姓名:聂成福  张文田  李松奎  张传文
作者单位:山东临沂地区沂水中心医院神经内科,山东临沂地区沂水中心医院神经内科,山东临沂地区沂水中心医院神经内科,山东临沂地区沂水中心医院神经内科 沂水 276400,沂水 276400,沂水 276400,沂水 276400
摘    要:本文报道2组脑血栓形成病人各57例,分别用胞磷胆碱和常规药物治疗。总有效率,胞磷胆碱组(84%)略高于常规药物组(77%),无显著性差异(P>0.05)。但治愈率,前者(37%)明显高于后者(14%),差异非常显著(P<0.01)。说明用胞磷胆碱治疗脑血栓形成能提高该病的治愈率,用药愈早疗效愈好。该药有催醒效果,未见明显不良反应。

关 键 词:胞磷胆碱  脑血管意外  网状结构  觉醒

Treatment of 57 patients of cerebral thrombosis with citicoline
NIE Cheng-Fu,ZHANG Wen-Tian,LI Song-kui,ZHANG Chuan-Wen. Treatment of 57 patients of cerebral thrombosis with citicoline[J]. Chinese Journal of New Drugs and Clinical Remedies, 1989, 0(4)
Authors:NIE Cheng-Fu  ZHANG Wen-Tian  LI Song-kui  ZHANG Chuan-Wen
Abstract:Cerebral thrombosis, 114 patients, divided equally at random into two groups.Citicoline was given to the first group, while routine remedies for the other. Clinical improvements were proved to be 84% with citicoline while 77% in the other. Certainly,it was statistically insignificant (P>0.05).On the other hand, as radical cure concerned, citicoline, 400-500 mg daily by intravenous infusion for 13.8(range 5-29)days was 37%, while the control 14% only. This indicated significantly citicoline is definitely superior than theordinary routine therapy (P<0.01). Clinically, citicoline is especially favoured for those early patients. There is an obvious effect of arousing from sleep and no remarkable side effects for citicoline.
Keywords:citicoline  cerebrovasclllar disorders  reticular formation  arousal  
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