前列腺偶发癌22例临床分析

目的:探讨前列腺偶发癌的临床和病理特征。方法:回顾1982年～1998年经耻骨上前列腺摘除术及经尿道电切术治疗的良性前列腺增生726例资料。结果:术后病理检出前列腺癌为22例,检出率为3.3%。其中A1期6例,A2期16例。高中分化腺癌占77.2%。病理学特征为在增生组织中存在单个或多个腺癌病灶。癌灶与增生组织分界不清,多数可见不典型增生。治疗:16例行双侧睾丸切除术。3年存活率为90%(20/22)。结论:偶发癌检出率低于国内其他报道。通过病理资料观察,提示前列腺癌发生发展变化的过程。提高早期前列腺癌的诊断,可以使其治疗达到满意的效果。

Clinical analysis of 22 cases with incidental adenocarcinoma of prostate

Objective To investigate the clinical and pathological features of incidental prostatic carcinoma. Method The records of 726 men with benign prostatic hyperplasia who underwent open prostatectomy and urethra electrocision between 1982 and 1998 were reviewed retrospectively. Results 22 cases of prostatic carcinoma were confirmed on pathological examination. The cancer detection rate was 3.3%. Among them 6 patients were A1stage and 16 were A2 stage. The moderately-differentiated carcinoma and poorly-differentiated carcinoma accounted for 77.2%. In hyperplasia tissues there were one or many focal lesion of adenocarcinoma. And the focal lesion and hyperplasia tissues delimitation was not clear. Prostate intraepithelial neoplasia could be seen in most of the cases. Bilateral orchiectomy was performed in 14 of them. The survival rate of three years was 90%(20/22). Conclusion incidental prostatic carcinoma detection rate is lower than other papers in our country. Through the pathological data, the occurrence and progressing procedure of prostatic carcinoma could been revealed. Early detection of prostatic carcinoma can improve the result of treatment.