急性心肌梗死早期（发病3h内）静脉溶栓治疗与急诊PCI术的临床疗效比较

目的针对急性心肌梗死早期患者（发病3h内）,分别进行静脉滴注国产尿激酶溶栓治疗和急诊行PCI术,对比分析两种治疗方法的临床疗效,并观察其不良反应。方法首次发生ST段抬高的AMI患者共229例,其中131例患者接受静脉溶栓治疗（溶栓组）,98例接受急诊介入治疗（急诊组）。两组均于发病3h内进行治疗;对比分析患者TIMI血流情况、治疗后主要心血管事件发生率等因素。结果梗塞相关血管再通率无显著性差异（P〉0.05）;两组院内死亡率、院内无事件生存率、2周后超声心动图结果比较,差异有统计学意义（P〉0.05）。结论急性心肌梗死患者早期（发病3h内）静脉滴注国产尿激酶进行溶栓治疗与急诊行PCI术作用相近。

The clinical curative effect comparison between acute myocardial infarction early(within 3 hours) intravenous thrombolytic therapy and emergency PCI surgery

Objective In patients with acute myocardial infarction（within 3 hours）,respectively,for intravenous infusion of urokinase thrombolytic therapy and emergency PCI operation,comparison and analysis of clinical effects of two treatment methods,and to observe the adverse reaction.Methods Of the first occurrence of ST segment elevation in AMI patients with a total of 229 patients,including 131 patients undergoing venous thrombolysis therapy（therapy group）,98 patients received interventional therapy（emergency group）.Two groups from the onset of treatment within 3 h;the mean age of patients,TIMI flow conditions,after treatment of 1 month within the major cardiovascular event rate and other factors were analyzed.Results Of the two groups of infarct related artery recanalization rate had no significant difference between（P 0.05）.The difference was statistically significant of inhospital mortality,hospital event free survival,two weeks after ultrasound heartbeat graph results（P 0.05）.Conclusion For patients with acute myocardial infarction early（within 3 hours） intravenous infusion of urokinase thrombolytic therapy and emergency PCI operation can be comparable to.