| 急性胰腺炎患者血浆vWF和IL-6的变化及临床意义 |
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| 引用本文： | 徐永居. 急性胰腺炎患者血浆vWF和IL-6的变化及临床意义[J]. 医学理论与实践, 2013, 0(24): 3230-3231,3236 |
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| 作者姓名： | 徐永居 |
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| 作者单位： | 扬州大学临床医学院苏北人民医院消化内科,江苏省扬州市225001 |
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| 摘 要： | 目的：探讨急性胰腺炎患者血浆vWF因子和]1,-6的变化及其l艋床意义。方法：应用ELISA法对重症急性胰腺炎组（24例）、轻型急性胰腺炎组（44例）及对照组（15例）血浆中的vWF因子和IL-6进行测定。结果：三组病例血浆中的vwF分别为（230．5士52．7）％、（175．8±30．3）oA、（84．5士21．3）％；IL-6分别为（68．76±28．62）ng／ml、（35．95土11．56）ng／ml、（14．46土3．53）ng／ml，三组之间差异显著（P〈O．05）。血浆vWF因子和IL-6预测重症AP的敏感性、特异性和准确性分别是96．7％、86．7Z、91．6oA和60％、90％、75％。结论；检测血浆vWF和IL-6的水平变化，对急性胰腺炎的早期诊断、病情判断和预后评估具有重要的应用价值。
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| 关 键 词： | 急性胰腺炎 白细胞介素-6血管性血友病因子 |
The Changes and Clinical Significance of Serum vWF and IL-6 in Acute Pancreatitis |
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| XU Yongju. The Changes and Clinical Significance of Serum vWF and IL-6 in Acute Pancreatitis[J]. The Journal of Medical Theory and Practice, 2013, 0(24): 3230-3231,3236 |
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| Authors: | XU Yongju |
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| Affiliation: | XU Yongju. Department of Gastroenterology, Clinical Medicine School of Yangzhou University, Yangzhou City, J iangsu Province 225001 |
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| Abstract: | Objective：To investigate the changes and clinical significance of serum vWF and IL-6 in acute pancreatitis （AP）. Methods：The serum levels of vWF and IL-6 in 24 cases of SAP,44 cases of MAP and 15 normal controls were determined by ELtSA. Results：The vWF and IL-6 in the 24 patients with SAP was significantly higher than that in 44 patients with MAP, and the 15 healthy volunteers （P〈 0. 05）, The sensitivity, specificity, correctly classified were 96.7% 86. 7% 91. 6% for vWF, and 60%, 90%, 75% for IL-6 in assessing the severity of pancreatitis. Conclusion： The determination of serum levels of vWF and IL-6 may be valuable for early diagnosis,judgment of severity and prog- nosis of acute pancreatitis. |
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| Keywords: | Acute pancreatitis Interleukin-6 von Willebrand factor |
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