| 滤除白细胞与MB-P法病毒灭活对血浆生化指标的影响 |
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| 引用本文： | 冯国基,刘鹏,杜学丽,梁继伟.滤除白细胞与MB-P法病毒灭活对血浆生化指标的影响[J].实用医药杂志(山东),2009,26(8):13-15. |
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| 作者姓名： | 冯国基 刘鹏 杜学丽 梁继伟 |
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| 作者单位： | 401医院输血科,山东青岛,266071 |
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| 摘 要： | 目的探讨应用滤除白细胞及MB-P病毒灭活技术对血浆生化指标的影响。方法随机采集无偿献血合格者血液标本20份,400ml/份。将每份新鲜血浆在制备过程中平均分为试验组与对照组。所有标本同时进行相关生化指标检测。结果试验组经滤除白细胞后FRUC浓度、FHb及CO2增高明显,与对照组比较有显著性差异(P<0.01)。试验组经MB-P法病毒灭活后FRUC与P3+浓度明显增高,FHb下降较快,与对照组及病毒灭活后比较均有显著性差异(P<0.01)。其它生化指标变化不大。结论滤除白细胞及病毒灭活后的血浆制作,对血液生化指标影响均较小或轻,适用于临床输用血(浆)需求。
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| 关 键 词： | 滤除白细胞 亚甲蓝光化学法 病毒灭活 血浆 生化 |
The impact of methylene blue plus light method for virus inactivation and leukocyte proof filter on plasma biochemistry indexes |
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| Abstract: | Objective To evaluate the impact of methylene blue plus light method for virus inactivation and leukocyte proof filter on plasma biochemistry indexes.Method Twenty blood sample were randomly taken out,400ml/share,dimidiated to trail group and control group.Biochemistry indexes of all the samples were analyzed at the same time.Result The levels of FRUC,CO2,FHb changed significantly(P<0.01) after filtration,whereas the levels of FRUC,P3+,FHb changed significantly(P<0.01) after methylene blue plus light.Conclusion The impact of methylene blue plus light method for virus inactivation and leukocyte proof filter on plasma biochemistry indexes are less;it is applicable for clinical blood transfusion. |
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| Keywords: | Leukocyte proof filter Methylene blue plus light Virus inactivation Plasma Biochemistry indexes |
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