| 肺和肺癌角蛋白免疫组化观察 |
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| 引用本文： | 李涤臣,曹光群,承泽龙,章可仪,葛霞,周序陇,陶仪声. 肺和肺癌角蛋白免疫组化观察[J]. 蚌埠医学院学报, 1989, 0(3) |
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| 作者姓名： | 李涤臣 曹光群 承泽龙 章可仪 葛霞 周序陇 陶仪声 |
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| 作者单位： | 蚌埠医学院病理解剖学教研室(李涤臣，曹光群，承泽龙，章可仪，葛霞，周序陇)，蚌埠医学院病理解剖学教研室(陶仪声) |
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| 摘 要： | 本文比较正常肺组织和肺癌多克隆角蛋白免疫组化标记结果。10例围产儿尸检肺和31例癌旁组织的正常支气管及较大分支均阳性,程度由近端向末梢逐渐递减。支气管腺体中,浆液性腺泡阳性。鳞癌39例,每例均可查见数量不等的强阳性细胞;这对Ⅲ级鳞癌的诊断很有价值。腺癌20例,呈中度或弱阳性反应,分布较均匀;腺样结构和粘液分泌仍为诊断依据。差分化癌17例和小细胞癌6例以弱阳性为主。还结合文献进行讨论。
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| 关 键 词： | 肺癌 角蛋白 免疫组化 |
IMMUNOHISTOCHEMIC OBSERVATION OF KERATIN IN HUMAN BRONCHUS AND LUNG CARCINOMA |
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| Li Dichen,et al.. IMMUNOHISTOCHEMIC OBSERVATION OF KERATIN IN HUMAN BRONCHUS AND LUNG CARCINOMA[J]. Journal of Bengbu Medical College, 1989, 0(3) |
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| Authors: | Li Dichen et al. |
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| Abstract: | This retrospective study evaluated the us; of immunoperoxidase stain for keratin in the diagnosis of lung cancer. It was performed on paraffin sections from 82 lung neoplasms, and the results were compared with those of the normal bronchus. Strong staining for keratin was evident in all squamous cell carcinomas (39 cases) . This reaction was particularly helpful in identifying squamous differentiation in poorly differentiated area of the tumour. Intermediate or weak positive stain could be seen in adenocarcinomas ( 20 cases ) , and weak positive stain in poorly differentiated carcinoma (13 of 17 cases) and small cell carcinoma (4 of 6 cases ) . |
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| Keywords: | lung neoplasm keratin iminunobistochemistry |
| 本文献已被 CNKI 等数据库收录！ |
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