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血清N末端B型钠尿肽原在不明原因呼吸困难病因分析中的临床意义
引用本文:陈杨,陈妍,吴丽平. 血清N末端B型钠尿肽原在不明原因呼吸困难病因分析中的临床意义[J]. 临床医学, 2010, 30(1): 4-5
作者姓名:陈杨  陈妍  吴丽平
作者单位:四川省攀枝花十九冶医院心内科,攀枝花,617023
摘    要:目的探讨血清N末端B型钠尿肽原(NT-proBNP)在不明原因呼吸困难病因分析的临床意义。方法针对急诊入院不明原因呼吸困难的患者,应用电化学发光法检测患者血清NT-proBNP的浓度;详细追问病史、体格检查,结合心电图、心脏彩超、胸片、肺功能测定等相关检查,进一步明确患者呼吸困难的原因。结果心源性呼吸困难患者血清NT-proBNP浓度在829.20~18700.50 pg/ml间,NT-proBNP呈偏态分布,中位数水平分别为4474.80 pg/ml,非心源性呼吸困难患者血清NT-proBNP浓度在10.20~389.50 pg/ml间,NT-pro BNP呈偏态分布,中位数水平分别为174.20 pg/ml,两组患者血清NT-proBNP浓度中位数比较差异有统计学意义(P值0.05)。结论血清NT-proBNP浓度在鉴别心源性或非心源性呼吸困难中有重要意义。

关 键 词:N末端B型钠尿肽原  呼吸困难  心源性  非心源性  血清

Significance of N-terminal pro-brain natriuretic peptide in analysis of dyspnea with unknown cause
CHEN Yang,CHEN Yan,WU Liping. Significance of N-terminal pro-brain natriuretic peptide in analysis of dyspnea with unknown cause[J]. Clinical Medicine, 2010, 30(1): 4-5
Authors:CHEN Yang  CHEN Yan  WU Liping
Affiliation:CHEN Yang,CHEN Yan,WU Liping.Department of Cardiology,the 19th Metallurgy Hospital of Panzhihua,Panzhihua 617023,China
Abstract:Objective To study the clinical significance of NT-proBNP in analysis of dyspnea with unkown cause. Methods To detect the serum densities of NT-proBNP by electrochemiluminescence for the patients with dyspnea of unknown cause on emergency admission.By tracing the detailed history of illness,physical examination,combined with the related tests of cardiogram,cardiac color doppler sonography,sternum,lung function to clarify the causes of dyspnea.Results The serum NT-proBNP densities of the cardiac dyspnea pati...
Keywords:N-terminal pro-brain natriuretic peptide  Dyspnea  Cardiac  Non-cardiac  Serum  
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