| t（8;21）急性髓细胞白血病：30例临床和实验室分析 |
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| 引用本文： | 肖志坚 郝玉书. t（8;21）急性髓细胞白血病：30例临床和实验室分析[J]. 中华血液学杂志, 1995, 16(4): 190-192 |
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| 作者姓名： | 肖志坚 郝玉书 |
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| 作者单位： | 中国医学科学院血液学研究所 |
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| 摘 要： | 报告３０例ｔ（８；２１）急性髓细胞白血病（ＡＭＬ），２６例为Ｍ＿（２ｂ），４例为Ｍ＿（２ａ）。初始完全缓解率为０．９６２。０．７６２的男性患者伴有－Ｙ，０．２２２的女性患者伴有－Ｘ，０．２６７的患者伴有其它染色体异常。免疫表型分析ＨＬＡ－ＤＲ／ＤＰ阳性率０．１００，ＣＤ＿（３８）为０．８６６，ＣＤ＿（１５）为０．５００，ＨＩＭ＿４、ＨＩＭ＿５均为０．８００。ｔ（８；２１）ＡＭＬ与ＡＭＬＭ＿（２ｂ）的关系需进一步深入研究。
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| 关 键 词： | 白血病，髓细胞性，急性，染色体异常，免疫表型 |
t(8;21) ACUTE MYELOID LEUKEMIA: AN ANALYSIS OF 30 CASES |
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| Xiao Zhijian, Hao Yushu, Li Jianbo,et al.. t(8;21) ACUTE MYELOID LEUKEMIA: AN ANALYSIS OF 30 CASES[J]. Chinese Journal of Hematology, 1995, 16(4): 190-192 |
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| Authors: | Xiao Zhijian Hao Yushu Li Jianbo et al. |
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| Affiliation: | Xiao Zhijian, Hao Yushu, Li Jianbo, et al. |
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| Abstract: | hirty patients with t( 8;21) acute myeloid leukemia( AML) were analyzed.Their morphological diagnosiswere M_(2b) in 26 and M_(2a) in 4 cases,respectively.Thecomplete remission rate after initial induction chemother-apy was 9 6.2%. Sex chromosome loss was found in76.2%of male and 22.2%of female patients. In26.7%of the cases there were other additional chromo-some abnormalities.For immunophenotypes,HLA-DR/DP was positive in 1 00%,CD_(38) in 86.5%, CD_(15) in 50. 5%,and HIM_4 and HIM_5 both in 80.0% patients. Therelationship between t ( 8;21) AML and AML M_(2b) isworth further researching. |
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| Keywords: | Leukemia myeloid acute AML-M_(2b) t( 8 21)(q22 q22)Im-munophenotype |
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