高容量血液滤过治疗脓毒症合并MODS临床应用

目的：探讨高容量血液滤过（HVHF）在脓毒症合并多器官功能障碍综合征（MODS）治疗中的临床疗效。方法：HVHF治疗6例脓毒症合并MODS患者，观察治疗前后患者血流动力学、呼吸参数等全身情况的变化及TISS评分、APACHE－II评分、MODS评分的变化。结果：6例经HVHF治疗后，血流动力学参数，TISS评分均有明显改善，APACHE－Ⅱ和MODS评分也有下降趋势。结论：HVHF可以改善全身感染合并MODS病人呼吸和循环功能，并有缓解病情，提高危重症病人生存率。

Application of High- volume Hemoflitration in the Treatment of Sepsis with MODS

Objective: To evaluate the clinical efficacy of high - volume hemoflitration in patients of sepsis with MODS (HVHF). Methods:Data of six patients of sepsis with MODS treated by HVHF were studied and observe the difference of hemodynamics,respiratory parameters and TISS scores, APACHE - a! scores , MODS scores before and after the therapy. Results: After the treatment by HVHF,patients' hemodynamic parameter and TISS scores apparently improved, APACHE -a! and MODS scores also descended. Conclusion: HVHF can improve respiratory and circulation function of patients with sepsis and MODS ,relieve the illness, and enhance the survival rate of critical patients.