Synthesis of 8-methyltheobromine from 3-methyl-4-aminouracil

A new three-step method has been developed for the synthesis of 8-methyltheobromine from 3-methyl-4-aminouracil, based on its bromination, the conversion of 3-methyl-4-amino-5-bromouracil to 3-methyl-4-amino-5-dimethylaminouracil, and the reaction of the latter with acetic anhydride.Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 1, pp. 23–25, January, 1967.