| 血浆胸腺基质淋巴细胞生成素在毛细支气管炎中的意义 |
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| 引用本文： | 张建青,杨龙,谭翠玲. 血浆胸腺基质淋巴细胞生成素在毛细支气管炎中的意义[J]. 国际医药卫生导报, 2017, 23(18). DOI: 10.3760/cma.j.issn.1007-1245.2017.18.007 |
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| 作者姓名： | 张建青 杨龙 谭翠玲 |
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| 作者单位： | 1. 511400,广州市番禺区何贤纪念医院儿科;2. 广东医科大学, 湛江,524000 |
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| 基金项目： | 广东省广州市番禺区科技计划项目(2014-Z03-05)Science and Technology Planning Project of Panyu District of Guangzhou City |
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| 摘 要： | 目的 探讨血浆胸腺基质淋巴细胞生成素(thymic stromal lymphopoietin,TSLP)在首次罹患毛细支气管炎患儿发病过程中的意义.方法 首次喘息,临床诊断为毛细支气管炎的患儿共50例,男34例,女16例,平均年龄(7.0±4.8)个月;同期体检健康的婴儿25例,男19例,女6例,平均年龄(7.2±4.0)个月.就诊婴儿分别于就诊当日采集3 ml外周静脉血,分离血浆,并采用ELISA法检测TSLP.结果 毛细支气管炎患儿血浆TSLP为(0.271±0.073) ng/ml,健康婴儿血浆TSLP为(0.211±0.084) ng/ml,差异有统计学意义(P＜0.05).结论 毛细支气管炎患儿血浆TSLP明显升高,TSLP参与毛细支气管炎的发病过程.
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| 关 键 词： | 胸腺基质淋巴细胞生成素 毛细支气管炎 患儿 |
Significance of plasma thymic stromal lymphopoietin in bronchiolitis patients |
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| Zhang Jianqing,Yang Long,Tan Cuiling. Significance of plasma thymic stromal lymphopoietin in bronchiolitis patients[J]. International Medicine & Health Guidance News, 2017, 23(18). DOI: 10.3760/cma.j.issn.1007-1245.2017.18.007 |
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| Authors: | Zhang Jianqing Yang Long Tan Cuiling |
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| Abstract: | Objective To explore the role of plasma thymic stromal lymphopoietin (TSLP) in newly detected bronchiolitis patients.Methods The levels of plasma TSLP in 50 infants with bronchiolitis [34 male and 16 female,the average age was (7.0±4.8) months] and 25 healthy infants [19 male and 6 female,the average age was (7.2±4.0) months] were detected by ELISA.Results The level of plasma TSLP in infants with bronchiolitis was (0.271±0.073) ng/ml,that in healthy infants was (0.211±0.084) ng/ml,with statistically significant difference (P＜0.05).Conclusion TSLP participates the pathogenesis ofbronchiolitis. |
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| Keywords: | Thymic stromal lymphopoietin Bronchiolitis Infants |
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