丹莪妇康煎膏用于盆腔炎性疾病后遗症的临床研究

目的 观察丹莪妇康煎膏治疗盆腔炎性疾病后遗症的临床疗效及对卵巢动脉、子宫动脉血液流变学的影响.方法 将45例盆腔炎性疾病后遗症患者随机分为治疗一组、治疗二组及对照组,治疗两组服用丹莪妇康煎膏,对照组服用克林霉素及甲硝唑,观察3组用药后临床效果及用药前后卵巢动脉、子宫动脉的血液动力学改变.结果 治疗一组治愈率为40.0％、总有效率为100.0％,治疗二组治愈率为46.7％、总有效率为93.3％,与对照组比较差异均有统计学意义;局部体征评分治疗组治疗后评分明显下降,与治疗前比较差异有统计学意义(P＜0.05),治疗两组与对照组治疗后评分比较,差异有统计学意义(P＜0.05);治疗两组治疗后卵巢动脉及子宫动脉的搏动指数、阻力指数较治疗前增高,差异有统计学意义(P＜0.05).结论 丹莪妇康煎膏治疗盆腔炎性疾病后遗症临床疗效好,剂量每次15g更适合患者病情需要,能够提高子宫及卵巢动脉的搏动指数、阻力指数,因此可作为评价活血化瘀中药治疗本病临床疗效的一个客观指标.

Dan'e Fukang cream for sequelae of pelvic inflammatory disease

Objective To observe the clinical effect of Dan'e Fukang cream for sequelae of pelvic inflammatory disease and its influence on the blood rheology of ovary and uterus arteries.Methods The 45 patients with sequelae of pelvic inflammatory disease were randomly divided into a treatment group A,a treatment group B,and a control group.Both treatment groups took Dan'e Fukang cream and the control group clindamycin and metronidazole.The clinical effects after the medication and the changes the blood rheology of ovary and uterus arteries before and after the treatment were observed.Results The cured rate and total effective rate were 40.0％ and 100.0％ in the treatment group A and were 46.7％ and 93.3％ in the treatment group B,with statistical differences from those of the control group.The local symptom score was lower after than before the treatment in both the treatment groups and were better in both the treatment groups than in the control group after the treatment,with statistical differences (P ＜ 0.05).and had significant difference compared with before treatment (P ＜ 0.05).The score of two treatment groups had significant difference compared with the control group (P ＜ 0.05).The pulsation indexes and resistance indexes of ovary and uterus arteries were higher after than before the treatment in both the treatment groups,with statistical differences (P ＜ 0.05).Conclusions Dan'e Fukang cream for sequelae of pelvic inflammatory disease is clinically effective;15 g per time is better for the patients can increase the pulsation indexes and resistance indexes of ovary and uterus arteries;therefore they can be used as objective indicators to evaluate the clinical effect of Chinese medicine activating blood circulation for the disease.