凋亡相关蛋白Bcl-2和Bax在慢性鼻及鼻窦炎伴嗅觉障碍患者嗅黏膜中的表达

目的 研究Bcl-2和Bax在慢性鼻及鼻窦炎(CRS)伴嗅觉障碍患者嗅黏膜中的表达,探讨其对嗅觉神经元(olfactory receptor neurons,ORNs)凋亡的调节作用.方法 采用康涅狄格化学感受临床研究中心所采用的嗅觉检查法——CCCRC (Connecticut Chemosensory Clini...

Strategies on treatment of inferior turbinate during the endoscopic nasal septal construction

OBJECTIVE To study the strategies on treatments of inferior turbinate during the endoscopic nasal septal construction.METHODS Clinical data of 62 patients with nasal septum deviation and inferior turbinate hypertrophy were analyzed,three kinds of operation were used according to the specific characteristics of different patients,and subjective symptoms were graded,using visual analogue scales(VAS method)before and after operations respectively.RESULTS According to the endoscopy and CT scans,all 64 patients had septum deviation,among which 28 patients were accompanied with mucosal hyperplasia of inferior turbinate and the other 34 patients with bony hyperplasia.The 28 patients with inferior turbinate mucosal hyperplasia accepted lowtemperature radiofrequency ablation.In the patients with bony hyperplasia,eighteen patients accepted inferior turbinate relocation and 16 patients accepted submucosal resection of inferior turbinate.After follow up for 3 to 6 months,symptoms were released in 22 cases,improved in 33 cases,and 7 cases had no effect.The effective rate was 88.71%,and there was a significant difference(t=12.452,P<0.01).CONCLUSION During the endoscopic septoplasty surgery,the treatment of inferior turbinate hyperplasia should be based on the different pathologic changes.