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| 帕金森病患者便秘发生情况的临床观察 | |
| 引用本文： | 胡晓,王省,闫福岭,刘卫国.帕金森病患者便秘发生情况的临床观察[J].东南国防医药,2013,15(4):332-334. |
| 作者姓名： | 胡晓 王省 闫福岭 刘卫国 |
| 作者单位： | 1. 南京安宁医院 2. 江苏省中西医结合医院神经内科,江苏南京,210028 3. 东南大学附属中大医院神经内科,江苏南京,210009 4. 南京医科大学附属脑科医院神经内科,江苏南京,210029 |
| 基金项目： | 国家自然科学基金资助项目，江苏省中医药管理局资助项目，南京市科技局资助项目 |
| 摘 要： | 目的观察帕金森病(Parkinsons disease,PD)患者便秘的发生率,探讨便秘发生的相关因素。方法观察219例PD患者便秘的发生率;所有患者均完成了简易智能精神状态检查量表(MMSE)、Hoehn-Yahr分期和统一帕金森病评分量表第三部分(UPDRSⅢ)、罗马Ⅲ标准的评估及抗帕金森病药物左旋多巴等效剂量(LED)的换算。分析PD患者便秘发生的相关因素。结果 219例PD患者中,便秘发生率为69.41%(152/219),PD患者服用抗帕金森病药物LED和UPDRSⅢ评分与便秘发生显著相关,相关系数(r)分别为0.186、0.195(P<0.01)。结论便秘是PD患者的常见症状,PD患者运动障碍症状重、服用抗PD药物剂量大是其危险因素。 |
| 关 键 词： | 帕金森病 便秘 相关因素 |
Clinic investigation of constipation in Parkinson's disease |
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| HU Xiao , WANG Xing , YAN Fu-ling , LIU Wei-guo.Clinic investigation of constipation in Parkinson's disease[J].Journal of Southeast China National Defence Medical Science,2013,15(4):332-334. | |
| Authors: | HU Xiao WANG Xing YAN Fu-ling LIU Wei-guo |
| Institution: | 1.Department of Neurology,Affiliated Zhongda Hospital of Southeast University,Nanjing,Jiangsu 210009,China;2.Department of Neurology,Jiangsu Province Hospital on Integration of Chinese and Western Medicine,Nanjing,Jiangsu 210028,China;3.Department of Neurology,Affiliated Nanjing Brain Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China |
| Abstract: | Objective To investigate the prevalence and correlation factors of constipation in Parkinsons disease.Methods We used mini-mental state examination（MMSE）,Hoehn-Yahr staging,Unified Parkinson Disease Rating Scale（UPDRS） part Ⅲ,RomeⅢ standard assess 219 PD patients.The Levodopa equivalent doses（LED） of PD patients were calculated.Results 152 PD patients exist constipation,the prevalence of constipation in Parkinsons disease was 69.41%（152 /219）,and correlation factors of LED and UPDRS Ⅲ scores were 0.186 and 0.195 respectively（P ＆lt; 0.01）.Conclusion Constipation is a common symptom in PD patients.The more severe motor symptom and higher LED is the risk factors in prevalence of constipation in Parkinsons disease. |
| Keywords: | Parkinson's disease constipation correlation factors |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |