脑猪囊尾蚴病临床及病理学特点

目的 探讨脑猪囊尾蚴病的临床及病理学特点.方法 回顾性分析13例脑猪囊尾蚴病患者的临床资料,并结合文献对其影像学、病理学进行分析.结果 本组13例患者中,11例以癫痫发作为主要症状;6例病理学检查均发现囊尾蚴虫体;9例病灶周围脑组织可见炎症反应;在病灶及其周围的脑组织中可见散在的石灰小体.头部CT检查表现为片状或点状低密度影,病灶区MRI表现为囊性异常信号.结论 脑猪囊尾蚴病首发症状以癫痫发作多见;影像学检查对脑猪囊尾蚴病诊断有帮助,但最后确诊需病理学检查;病理学检查除找到囊尾蚴虫体外,脑组织中发现散在的石灰小体是诊断陈旧性病变的重要依据.

Clinicopathological observation of neurocysticercosis (analysis of 13 cases)

Objective To investigate the imaging and clinicopathologic features of neurocysticercosis. Methods The clinical data of 13 patients with neurocysticercosis were analyzed retrospectively, including the clinical manifestation and imaging data. The literatures related to the neurocysticercosis were reviewed. Results The ages of the patients ranged from 16 to 32 years (mean age, 21 years). The epileptic seizure was main symptom in 11 patients with neurocysticercosis. The inflammation reaction in the cerebral tissues surrounding the foci was found in 9 patients. The cysticercul bodies were found in 6 patients. There were scattered calcareous bodies in the necrotic area. CT scan showed that there were patchy or punctiform low density areas and there were abnormal signals on MRI in the cerebral tissues of the patients with neurocysticercosis. Conclusions Epilepsy is the common symptom in the patients with neurocysticercosis. The imaging findings is helpful to the diagnosis of neurocysticercosis, but its definite diagnosis needs pathological examination by which the cysticercus and calcareous bodies, important proofs of the old pathological changes of neurocysticercosis may be found in the cerebral tissues of the patients with neurocysticercosis.