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正交设计优选碎米糖化液的脱色工艺
引用本文:石继连,刘文龙,杨岩涛,邓凯文,陈锋,唐昱,贺福元.正交设计优选碎米糖化液的脱色工艺[J].中国医药导报,2012,9(3):117-118,125.
作者姓名:石继连  刘文龙  杨岩涛  邓凯文  陈锋  唐昱  贺福元
作者单位:1. 湖南中医药大学药学院,中药药性与药效国家中医药管理局重点实验室,湖南长沙410208
2. 湖南中医药大学第一附属医院,湖南长沙,410007
基金项目:湖南省科技厅科研课题(项目编号:2010SK3019)
摘    要:目的优选碎米糖化液脱色的最佳工艺条件。方法以活性炭为脱色剂,在单因素基础上进行正交试验,对碎米糖化液进行活性炭用量、加热温度和脱色时间等因素的考察,以葡萄糖保留率和脱色率为指标,选择最佳工艺。结果碎米糖化液活性炭脱色的最佳工艺为:糖化液加入3%的活性炭后,在70℃下脱色40 min。结论本文所建立的脱色工艺简单可行,可为进一步制备注射用葡萄糖的脱色工艺研究提供实验依据。

关 键 词:碎米  糖化液  葡萄糖  脱色  工艺  正交设计

Optimization of decoloration technology of saccharification liquid from broken rice by orthogonal design
SHI Jilian,LIU Wenlong,YANG Yantao,DENG Kaiwen,CHEN Feng,TANG Yu,HE Fuyuan.Optimization of decoloration technology of saccharification liquid from broken rice by orthogonal design[J].China Medical Herald,2012,9(3):117-118,125.
Authors:SHI Jilian  LIU Wenlong  YANG Yantao  DENG Kaiwen  CHEN Feng  TANG Yu  HE Fuyuan
Institution:1.School of Pharmacy,Hu′nan University of Chinese Medicine,the Key Laboratory of Traditional Chinese Medicine in Medicinal Properties and Efficacy of the State Administration of Traditiomal Chinese Medicine,Hu′nan Province,Changsha 410208,China;2.The First Affiliated Hospital of Hu′nan University of Chinese Medicine,Hu′nan Province,Changsha 410007,China
Abstract:Objective To optimize the decoloring technology conditions of saccharification liquid from broken rice.Methods Taking the active carbon as decoloring agents,the orthogonal experiments was performed on the single factor basis,with the purpose of investigation in the active carbon dosage,heating temperature and decoloring time of saccharification liquid from broken rice,glucose reserve rate and the decoloring rate were taken as the indexes to optimize the discolored technology.Results The optimum decoloring conditions of saccharification liquid from broken rice was 3% active carbon,with decoloring of 40 min under 70℃.Conclusion The decoloring technology is simple,practicable and available.It can provide experimental basis for the further decoloring technology research on the glucose injection.
Keywords:Broken rice  Saccharification liquid  Glucose  Decoloration  Technology  Orthogonal design
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