非糖尿病终末期肾病患者血液透析期间血糖变化

目的 探讨非糖尿病终末期肾病患者血液透析过程中血糖变化并分析其原因.方法 选取我院非糖尿病终末期肾病血液透析患者20例,其中非进食组11例,进食组9例(于透析1.5～2h进食).测定患者血液透析0、0.5、1.0、2.0、4.Oh时血糖浓度.收集患者透析废液,检测其中葡萄糖含量.结果 20例患者均未出现低血糖反应,其中非进食组2例患者出现无症状低血糖.进食组血糖呈逐渐增高趋势,而非进食组血糖呈逐渐降低趋势.进食组透析废液中葡萄糖丢失量为(17.70±6.33)g,非进食组透析废液葡萄糖丢失量为(15.43±8.52)g,两组比较差异无统计学意义.结论 非糖尿病肾病血液透析期间有低血糖发生风险,血液透析中葡萄糖丢失是其主要原因,建议非糖尿肾病血液透析患者使用含糖透析液,以减少低血糖发生风险.

Blood glucose level during hemodialysis in non-diabetic patients with end-stage renal disease

Objective To observe the level of blood glucose during hemodialysis in non-diabetic patients with end-stage renal disease.Methods Twenty non-diabetic patients were collected and assigned to group Ⅰ (n =11,food intake was prohibited in the process of hemodialysis) and group Ⅱ (n =9,food intake was allowed at 1.5 to 2.0 hours after hemodialysis).During hemodialysis,the blood glucose at 0,0.5,1.0,2.0 and 4.0 hours was measured.The glucose of waste dialysate was measured in all the patients.Results Overt hypoglycemia was occurrent in none of the patients during hemodialysis,although two patients presented occult hypoglycemia in the fasting group.In the food taken group,the blood glucose rised gradually and dropped in the other group.In the food taken group,the loss of glucose in waste dialysate was (17.70 ± 6.33)g.In the fasting group,the loss of glucose in waste dialysate was (15.43 ± 8.52)g.There was no significant difference between the two groups.Conclusion There may be the risk of hypoglycemia during hemodialysis in non-diabetic renal patients.The loss of glucose during hemodialysis could be the main reason of hypoglycemia.The use of dialysate with glucose can reduce the risk of hypoglycemia in non-diabetic patients with end-stage renal disease.