肿瘤相关性高凝的分子机制

恶性肿瘤在其发生、局部浸润、远处转移的过程中会产生一系列分子改变,这些基因突变或表达异常的分子对机体中血液的高凝起到了促进作用,同时血液高凝也会增加肿瘤发展的几率,了解二者发生的具体过程及发生过程中各分子扮演的角色可为临床医师更好地管理相关患者提供理论依据,对于研发更有效、更安全的新型口服抗凝药物也具有重要意义.

Molecular mechanism of tumor associated hypercoagulability

The process of tumorigenesis,local invasion and distant metastasis will produce a series of molecular changes,these genetic mutation or abnormal expression of molecules play a promoting role in hypercoagulation.At the same time,hypercoagulation also increases the risk of tumor progression.It is important to understand their specific processes and the molecular role,and it can provide theoretical basis for better management of patients,and has significance for developing more effective and security new anti-clotting drugs.