脾切除术后患者的血液学改变及血栓防治的研究进展

脾脏为腹部损伤中极易受损的器官,多数外伤性脾损伤患者需接受脾切除术.肝硬化失代偿期及部分血液病患者亦需行脾切除术,以达到治疗疾病或缓解病情的目的.脾切除术后患者的机体会发生一系列改变,其中血液学改变尤为显著,短期内又以血小板计数增高为突出表现,并且伴随着明显的血液高凝状态.因此,术后血栓形成又是危及患者生命的严重并发症之一.笔者拟就近年来有关脾切除术后患者的血液学改变及血栓的防治进行综述.

Research progress of hematological changes and control of thrombosis in patients after splenectomy

The spleen is such an organ which is vulnerable in abdominal injury.A majority of patients with traumatic spleen injury need splenectomy.Splenectomy is also necessary for patients with decompensated cirrhosis or certain blood disease to cure or alleviate the disease.The body will experience a series of changes after splenectomy,in which hematological change is so obvious,and the rise of blood platelet count is most outstanding event in short term coming with an obvious hypercoagulable state.Postoperative thrombosis is one of the most serious complications which may threaten patients' life.Therefore,this article reviewed literatures on hematological changes and prevention and treatment of thrombosis after splenectomy in recent years.