雄激素性脱发的遗传学研究现状 |
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引用本文: | 张俪,严月华.雄激素性脱发的遗传学研究现状[J].国际遗传学杂志,2016(6):344-349. |
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作者姓名: | 张俪 严月华 |
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作者单位: | 武汉大学中南医院皮肤科,430071 |
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基金项目: | 湖北省自然科学基金(2014 CFB470)@@@@Natural Science Foundation of Hubei Province of China (2014 CFB 470) |
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摘 要: | 雄激素性脱发( androgenic alopecia , AGA )是常见的脱发类型,研究显示与遗传相关,是一种激素依赖的、多种基因和环境因素共同作用的遗传性疾病。目前致病机制的研究主要集中于雄激素及雄激素受体。此外,一些遗传易感基因和易感位点也证实与该病有关。
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关 键 词: | 雄激素性脱发 遗传学 基因 单核苷酸多态性 |
A review of genetic researches of and rogenic alopcia |
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Abstract: | Androgenic alopecia ( AGA ) is a common type of hair loss .Studies have shown that this alopecia is associated with genetic factor .AGA is a genetic disease depending on hormone levels , multiple genes and environmental factors .Current researches of its pathogenic mechanism focus on andro-gen and androgen receptors .In addition , some susceptibility genes and single nucleotide polymorphisms are also confirmed related to AGA . |
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Keywords: | Androgenic alopecia Genetics Gene Single nucleotide polymorphism |
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