| 高效液相色谱法测定双扑伪麻片中扑热息痛、盐酸伪麻黄碱、扑尔敏的含量 |
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| 引用本文： | 魏万峰,王炜,李光耀.高效液相色谱法测定双扑伪麻片中扑热息痛、盐酸伪麻黄碱、扑尔敏的含量[J].沈阳药科大学学报,1999,16(3):10. |
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| 作者姓名： | 魏万峰 王炜 李光耀 |
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| 作者单位： | 海南三叶药物研究所,海口,570226 |
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| 摘 要： | 用高效液相色谱法，同时分离测定双扑伪麻片中扑热息痛、盐酸伪麻黄碱和扑尔敏的含量．线性范围：扑热息痛０２０～０８０ｇ／Ｌ，ｒ＝０９９９５；盐酸伪麻黄碱００１２～００４８ｇ／Ｌ，ｒ＝０９９９６；扑尔敏００００７２～０００２８８ｇ／Ｌ，ｒ＝０９９９２．平均回收率（ｘ±ｒｓｄ）％分别为：扑热息痛（１００２±１７）％；盐酸伪麻黄碱（９９６±１４）％；扑尔敏（９８４±２６）％．
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| 关 键 词： | 高效液相色谱 双扑伪麻片 扑热息痛 盐酸伪麻黄碱 扑尔敏 |
| 修稿时间： | :1998-03-2 |
HPLC Determination of the Content of Paracetamol,Pseudoephedrine Hydrochloride and Chlorphenamine Maleate in Pseudoephedrine Hydrochloride Compound Tablets |
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| Wei Wanfeng,Wang Wei,Li Guangyao.HPLC Determination of the Content of Paracetamol,Pseudoephedrine Hydrochloride and Chlorphenamine Maleate in Pseudoephedrine Hydrochloride Compound Tablets[J].Journal of Shenyang Pharmaceutical University,1999,16(3):10. |
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| Authors: | Wei Wanfeng Wang Wei Li Guangyao |
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| Abstract: | A HPLC method was used to determine the content of the three components in pseudoephedrine hydrochloride compound tablets.A better linearity and good correlation coefficient were obtained from 0\^20 g/L0\^08 g/L of paracetamol(r=0\^999 5);0\^012 g/L0048 g/L of pseudoephedrine hydrochloride(r=0\^999 6);0\^000 72 g/L0\^002 88 g/L of chlorphenamine maleate(r=0\^999 2).The mean recoveries and RSD of the three components were (100\^21\^7)%,(99\^61\^4)%,(98426)% respectively.The method is accurate,rapid and simple and can be used for the quantitive analysis of pseudoephedrine hydrochloride compound tablets. |
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| Keywords: | HPLC Pseudoephedrine hydrochloride compound tablets paracetamol pseudoephedrine hydrochloride chlorphenamine maleate |
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